Scaling Python Web Apps: Insights from Real Python

Is your infrastructure ready for AI-powered workloads with real-time video, audio, and chat?

In Episode 254 of The Real Python Podcast, Six Feet Up CTO and AWS Hero Calvin Hendryx-Parker joins host Christopher Bailey to explore what it really takes to scale modern Python web applications.

The conversation focuses on supporting high-demand, real-time experiences — including AI chatbots, video, and audio — and the infrastructure strategies required to ensure performance, reliability, and cost-efficiency at scale.

Calvin draws from a recent Six Feet Up project that delivered scalable AI personas capable of handling thousands of simultaneous user sessions. He outlines how his team used Kubernetes, Karpenter, and a streamlined dev-to-prod workflow to meet the challenge.

Whether you're preparing for a go-to-market launch or rethinking your infrastructure for scale, this episode delivers actionable insights for engineering leaders and dev teams alike.

Strategies for Scaling

1. Autoscale with Kubernetes + Karpenter

• Handle dynamic, high-volume workloads by autoscaling pods and infrastructure intelligently. Leverage spot instances and EC2 flexibility for cost-efficiency.‍

2. Avoid Hidden Infrastructure Bottlenecks

• Real-world scaling can break down due to unexpected constraints like pod IP limits. Observability helps identify and resolve issues before they impact users.‍

3. Boost Dev-to-Prod Velocity

• Adopt a consistent infrastructure blueprint — like Scaf™ — to align local dev environments with staging and production.‍

4. Invest in Full-Stack Observability

• Tools like Prometheus, Grafana, and Loki make it easier to monitor, debug, and optimize your Kubernetes workloads in real-time.‍

5. Future-Proof with Reusable Infrastructure Patterns

• Treat your infrastructure like a work of art: opinionated, documented, and modular. Reusable infrastructure helps teams iterate faster and reduce operational overhead.

If you're navigating the challenges of scaling modern, AI-driven applications, Calvin’s deep dive into Kubernetes, cloud architecture, and developer experience offers practical guidance and proven strategies to help you succeed.

Ready to build infrastructure that scales with confidence? Explore Six Feet Up’s AI expertise.

Listen to the Full Episode

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